It also may keep some medicines from working as well as they should, such as: If your health care provider tells you it's OK to use an herbal supplement along with medicine, be careful. The table below contains some of the most common ones associated with isosorbide mononitrate. include protected health information. All rights reserved. Registered in England and Wales. 19 are major, 174 are moderate, and 2 are minor. Available for Android and iOS devices. Daily headaches are a common side effect. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, List Isosorbide Mononitrate side effects by likelihood and severity. Let your provider know if you are using any medications for erectile dysfunction before you start taking isosorbide mononitrate (Monoket). Cleophas TJ, Niemeyer MG, Zwinderman AH, van der Wall EE. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. It will not treat an angina attack that has already begun. If tolerance is suspected during the use of transdermal patches they should be left off for 8-12 hours (usually overnight) in each 24 hours; in the case of modified-release tablets of isosorbide dinitrate (and . Isosorbide mononitrate belongs to the group of medicines called nitrates. Nitrates (eg, isosorbide dinitrate, isosorbide mononitrate, nitroglycerin). Unable to load your collection due to an error, Unable to load your delegates due to an error. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. You could also spray your face with cool water or sip non-alcoholic cold or iced drinks. 1994 Jan;15(1):108-13. doi: 10.1093/oxfordjournals.eurheartj.a060361. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. Vascular dilatation can precipitate venous pooling with decreased return to the heart, hypotension and reflex tachycardia. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.AvanafilRiociguatSildenafilTadalafilVardenafil. Moderately clinically significant. Never give it to other people even if their condition appears to be the same as yours. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Background: Some brands of isosorbide mononitrate tablets should be taken two or three times a day. other information we have about you. This medicine is a white, round, scored, tablet imprinted with "KU 107" and "20". Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. Duplication for commercial use must be authorized by ASHP. This should pass after a few days. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. Never take more than the prescribed dose. It is used to treat and prevent a wide range of different conditions. Isosorbide mononitrate - Wikipedia My blood pressure, cholesterol and pulse are all normal and I have no chest pains, shortness of breath or other heart problem symptoms. Do not use medications containing isosorbide dinitrate while using isosorbide mononitrate. Liperoti R, et al. Herbal supplements can interact with medicines used to treat heart and blood vessel problems, such as high blood pressure and heart failure. This content does not have an English version. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Isosorbide mononitrate (Monoket) is available as a generic medication and may be significantly cheaper compared to the brand version. http://www.upandaway.org. Your doctor will tell you which is the right dose for you, and this will also be printed on the label of the pack to remind you about what the doctor said to you. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Some side effects may occur that usually do not need medical attention. Some of these interactions can be life-threatening. What is the difference between the immediate-release (IR) and extended-release (ER) versions of isosorbide mononitrate (Monoket)? Dated August 2017. Make sure laboratory personnel and all your doctors know you use this drug. Isosorbide controls chest pain but does not cure coronary artery disease. It is important to take the drug at the same times each day. Accessed Sept. 7, 2022. In the remainder of them there was a highly significant time effect: the overall numbers of headache attacks in the first period of active treatment versus the second were 2,380 vs 1,400 (P < 0.003). Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Data were assessed for carryover and time effects. Isosorbide mononitrate Alternatives Compared - Drugs.com Watch for any symptoms that you may be having a drug interaction, such as: Mayo Clinic does not endorse companies or products. This medicine is for you. It might help to keep the room cool and use a fan. This content does not have an Arabic version. It can cause your blood pressure to become dangerously low. Consult your doctor for more details. Alcohol will increase the risk of you experiencing side-effects such as feeling dizzy and light-headed. These side effects may go away during treatment as your body adjusts to the medicine. Canada residents can call a provincial poison control center. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Tell your doctor right away if you have any serious side effects, including: fainting, fast/irregular/pounding heartbeat. Lyrica and Metoclopramide drug interaction, Calcitriol and Metoclopramide drug interaction. https://naturalmedicines.therapeuticresearch.com. But only about 25% of people who take herbal supplements tell their health care providers. May also be prescribed off label for Esophageal Spasm. The short-acting tablet is usually taken as 10 mg to 40 mg by mouth 2 or 3 times daily with at least a 14 hour period of time per day where you don't take any doses. This list covers only some interactions. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: continuing ringing or buzzing or other unexplained noise in the ears, dull ache or feeling of pressure or heaviness in the legs, excess air or gas in the stomach or intestines, increased sensitivity of the eyes to sunlight, loss in sexual ability, desire, drive, or performance, pain or tenderness around the eyes and cheekbones, redness of the face, neck, arms, and occasionally, upper chest, redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid, redness, swelling, or soreness of the tongue, small clicking, bubbling, or rattling sounds in the lung when listening with a stethoscope, stomach bloating, burning, cramping, or pain, terrifying dreams causing sleep disturbances, uncontrolled twisting movements of the neck, white patches in the mouth, tongue, or throat. This medicine is available only with your doctor's prescription. Journals of the American College of Cardiology. Many common herbal supplements interact with common heart medicines. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Your health care provider and pharmacist can help you stay away from unsafe interactions. Always consult your healthcare provider. It does not have such side effects. Isosorbide Mononitrate - Uses, Side Effects, Substitutes, Composition Would you like email updates of new search results? Pregnancy:Data on the use of isosorbide mononitrate during pregnancy are insufficient to be able to assess the possible harmful effect. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. Check with your doctor immediately if any of the following side effects occur: burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings, dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, fast, slow, irregular, pounding, or racing heartbeat or pulse, itching, pain, redness, or swelling on the leg, numbness or tingling in the hands, feet, or lips, pain or discomfort in the arms, jaw, back, or neck, pain, tension, and weakness upon walking that subsides during periods of rest, shakiness in the legs, arms, hands, or feet, swelling of the face, fingers, feet, or lower legs, trembling or shaking of the hands or feet, vomiting of blood or material that looks like coffee grounds, Bluish-colored lips, fingernails, or palms. it is a safe and effective alternative; the choice between beta blockers and calcium channel blockers depends . Healthcare data is obtained from a number of sources including the Food and Drug Administration (FDA). It works to relax your blood vessels. and transmitted securely. To provide you with the most relevant and helpful information, and understand which During pregnancy, this medication should be used only when clearly needed. Longer-acting tablets and capsules are taken once daily in the morning. Keep this medication in the container it came in, tightly closed, and out of reach of children. Imdur vs. Isordil - RxList [2] Prescription and OTC Aspirin relieves pain and inflammation and helps to thin the blood. This is called a medicine interaction. Get emergency help immediately if any of the following symptoms of overdose occur: bulging soft spot on the head of an infant, change in the ability to see colors, especially blue or yellow, feeling of constant movement of self or surroundings. There are 195 drugs known to interact with Integrative medicine (complementary and alternative medicine). We study 23,548 Isosorbide mononitrate users. 46 ratings on Drugs.com. The drug donates nitric oxide to the body, which is similar to all other Isosorbide mononitrates. There are no data on passage of isosorbide mononitrate in human milk, but some excretion seems likely. Call your doctor if you have any unusual problems while you are taking this medication. https://www.uptodate.com/contents/search. Do not stop taking isosorbide without talking to your doctor. Overview of herbal medicines and dietary supplements. the unsubscribe link in the e-mail. You can take your doses either before or after meals. We asked 34 people what they think about isosorbide mononitrate (Monoket): Get Isosorbide mononitrate (Monoket) for as low as $29.86, 180 tablets of isosorbide mononitrate 10mg. health information, we will treat all of that information as protected health Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. If you notice other effects not listed above, contact your doctor or pharmacist. Herbal supplements can strongly affect the body. The body tends to develop a tolerance (decreased sensitivity) to ISMN when it is used continuously over 24 hours. Some products have ingredients that could worsen your heart failure. Isosorbide mononitrate helps to prevent angina chest pain from developing. 2023 eHealthMe.com. Minimally clinically significant. Isosorbide mononitrate is used to prevent chest pain (angina) in patients with a certain heart condition (coronary artery disease). The narrowing makes it more difficult for blood to flow to your heart muscle. Epub 2006 Mar 22. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Side effects : headache, mild dizziness Many herbal supplements can interact with prescription drugs. Bookshelf Isosorbide mononitrate 30% immediate-release 70% sustained-release formulation: a review. https://naturalmedicines.therapeuticresearch.com. Isosorbide mononitrate, sold under many brand names, is a medication used for heart-related chest pain ( angina ), heart failure and esophageal spasms. You may report side effects to the FDA at 1-800-FDA-1088. Herbal supplements and heart medicines may not mix - Mayo Clinic 7.6 out of 10 from a total of This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction. Receive price alerts, news, and other messages from GoodRx about isosorbide mononitrate (Monoket) and other healthcare topics and relevant savings offers. Take the missed dose as soon as you remember it. Profen and Metoclopramide drug interaction, Metoclopramide and Nitrostat drug interaction, Metoclopramide and Alfentanil drug interaction, Risperdal and Metoclopramide drug interaction. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. 55 ratings on Drugs.com. This chest pain can feel more intense or painful than it was before you began taking isosorbide mononitrate (Monoket). The American Society of Health-System Pharmacists, 4500 East-West Highway, Suite 900, Bethesda, Maryland. Accessed Sept. 7, 2022. All rights reserved. Talk to your doctor or pharmacist about lifestyle changes that might benefit you. Follow directions about how much medicine to take. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. https://naturalmedicines.therapeuticresearch.com. FOIA All rights reserved. See also: aspirin side effects in more detail. Isosorbide immediate-release tablets are used for the management of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). It also relaxes and widens blood vessels in your heart (coronary arteries) which increases the flow of blood to your heart muscle. This medication performs a vasodilatory function and is therefore used as a treatment for high blood pressure. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Talk to your provider if you notice your chest pain starts to get worse. St. Joseph 81 mg Aspirin Enteric Safety-Coated. Reduction of blood-nitrate concentrations to low levels for 4 to 12 hours each day usually maintains effectiveness in such patients. Lifestyle changes such as dietary changes, exercise, and not smoking may help this drug work better. Herbal supplements and heart medicines may not mix, Your blood pressure, if you also take a drug to treat high blood pressure, Beta blockers, such as atenolol (Tenormin), nadolol (Corgard) or propranolol (Inderal LA, Innopran XL), Calcium channel blockers, such as diltiazem, nifedipine (Procardia) and verapamil (Calan SR, Verelan), Nitrates, such as nitroglycerin (Nitrostat, Nitro-Dur, others) and isosorbide (Isordil, Bidil), Statins, such as atorvastatin (Lipitor), lovastatin (Altoprev) and rosuvastatin (Crestor), Anti-rejection medicine, also called immunosuppressant medicine, such as cyclosporine (Gengraf, Neoral, Sandimmune). If concomitant therapy cannot be avoided, monitor clinical effects of the . flushing - try to cut down on coffee, tea and alcohol because they can make flushing worse. It is important that you follow the instructions your doctor gives to you about when to take your doses. Isosorbide mononitrate Alternatives Compared Isosorbide mononitrate Aspirin Nitroglycerin Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. It works by relaxing the blood vessels so the heart does not need to work as hard and therefore does not need as much oxygen. Zhonghua Yi Xue Za Zhi (Taipei). Please note that only the generic name of each medication is listed below. In: Current Medical Diagnosis & Treatment 2022. 8.0 out of 10 from a total of Isosorbide mononitrate dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.Isosorbide mononitrate is used to prevent angina attacks (chest pain). Egton Medical Information Systems Limited has used all reasonable care in compiling the information but make no warranty as to its accuracy. It works more slowly and lasts for about 12 hours, so you only need to take it once a day. This does not necessarily mean no interactions exist. See also: nitroglycerin side effects in more detail. This information is aggregated and used to produce personalized reports that patients can reference. Many people using this medication do not have serious side effects. Although unlikely, when this medication is used for a long time, it may not work as well and may require different dosing. Does Isosorbide Mononitrate interact with other drugs you are taking? The most common side-effect is headache. Headaches can be a sign that the medicine is working, and they might lessen with continued use of the medication. This is not a complete list of possible side effects. https://naturalmedicines.therapeuticresearch.com. It's usually not a problem for most people unless you drink alcohol or take other medications that can also lower your blood pressure. Isosorbide may not work as well after you have taken it for some time or if you have taken many doses. This is because the tablets/capsules are specially made to release the medicine they contain in a controlled way. Isosorbide mononitrate - UpToDate The https:// ensures that you are connecting to the Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. Isosorbide extended-release (long-acting) tablets and extended-release capsules are used for the management of chest pain in people who have coronary artery disease. Diabetes treatment: Can cinnamon lower blood sugar? We don't support your browser. Accessed Sept. 7, 2022. 2010; doi:10.1016/j.jacc.2009.07.074. Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. Patients were randomized to either 60 mg 5-ISMN once daily (od) for two weeks or to 30 mg 5-ISMN od for one week followed by 60 mg 5-ISMN od for one week. My EKG showed Assess your symptoms online with our free symptom checker. Contact your provider right away if you feel as if you are going to pass out and are experiencing an irregular heartbeat, nausea, vomiting, changes in vision, more sweating, or cold and clammy skin. [2] It can be used both to treat and to prevent heart-related chest pain; however, it is generally less preferred than beta blockers or calcium channel blockers. Some conditions may become worse when the drug is suddenly stopped. If you notice any other effects, check with your healthcare professional.Call your doctor for medical advice about side effects. Prescription and OTC Aspirin relieves pain and inflammation and helps to thin the blood. Yet many herbal supplements may interact with heart disease medicines. Mayo Clinic; 2021. Prescribed for Angina, Anal Fissure and eCollection 2021. Isosorbide mononitrate is used to prevent angina (chest pain) caused by coronary artery disease (heart disease). What are the side effects of Isosorbide Mononitrate ? 2006 Apr;95(4):217-23. doi: 10.1007/s00392-006-0367-x. Do not double the dose to catch up. Your doctor will prescribe you a short-acting nitrate for you to take if this happens. Which drugs or supplements interact with isosorbide mononitrate? It might help to take isosorbide mononitrate and dinitrate after meals.